The study evaluated a novel plug-and-play EUS system (EndoSound EVS) deployed in an ambulatory surgical center (ASC), which successfully expanded patient access to EUS procedures. Using the novel system, the practice saw a 29.2% increase in overall case volume and a 64.2% year-over-year growth for a single gastroenterologist. The system enabled safe and effective EUS examinations across various indications, reduced hospital burdens, increased ASC revenue, and provided more scheduling flexibility for physicians. Notably, all 42 ASC patients underwent EUS exams without complications, with image quality deemed excellent.